Table 1.
Sequential measurements of ITSS scoring and Q in the treated and control groups and P values for comparisons between different time points.
| Parameter | Treated group | Control group | ||||||
|---|---|---|---|---|---|---|---|---|
| Measurement | P valuesa | Measurement | P valuesa | |||||
| 7 days | 14 days | 21 days | 7 days | 14 days | 21 days | |||
| ITSS scoring [median (P25, P75)] | ||||||||
| Baseline (n = 5) |
1 to 2 [1 (1,1.5)] |
0.699 | 0.043 | 0.009 | 1 to 2 [1 (1,1.5)] |
0.007 | 0.006 | 0.005 |
| 7 days (n = 5) |
1 to 1.5 [1 (1,1.5)] |
0.051 | 0.008 | 2 to 3 [3 (2.5,3)] |
|
0.042 | 0.015 | |
| 14 days (n = 5) |
1 to 3 [2.5 (1.5,2.75)] |
0.381 | 3 to 4 [4 (3,4)] |
|
0.513 | |||
| 21 days (n = 5) |
2 to 3 [2.5 (2.25,3)] |
3 to 4 [4 (3.5,4)] |
|
|||||
|
| ||||||||
| Q (means ± SD) | ||||||||
| Baseline (n = 5) |
0.130 to 0.307 (0.203 ± 0.065) |
0.028 | 0.347 | 1.000 | 0.130 to 0.307 (0.203 ± 0.065) |
0.076 | 0.016 | 0.016 |
| 7 days (n = 5) |
0.063 to 0.160 (0.122 ± 0.038) |
0.028 | 0.014 | 0.209 to 0.374 (0.295 ± 0.059) |
|
0.175 | 0.251 | |
| 14 days (n = 5) |
0.130 to 0.222 (0.175 ± 0.033) |
0.462 | 0.271 to 0.385 (0.344 ± 0.047) |
0.917 | ||||
| 21 daysb | 0.170 to 0.207 (0.188 ± 0.017) |
0.263 to 0.429 (0.349 ± 0.060) |
|
|||||
aData were tested with Kruskal Wallis test followed by Mann–Whitney U test in case of statistical significance. bThere are 4 mice in the treated and 5 mice in the control group at 21 days for Q evaluation; ITSS, intratumoral susceptibility signal; SD, standard deviation.