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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Wiley Interdiscip Rev Comput Mol Sci. 2017 Apr 19;7(5):e1309. doi: 10.1002/wcms.1309

Figure 10. Search space increases exponentially with protein size.

Figure 10

Bigger computers alone have not been the solution to the game of Go nor to protein folding. Alternative algorithms that can incorporate intuition and current knowledge can help improve the scaling92.