Table 1. Volumes of the different ROIs based on high-resolution anatomical MRI.

N = 10 rats per group. Data represents mean ± SEM in μl and was analyzed using 2-way ANOVA with MD and mifepristone treatment as main factors. Statistical significance based on p-values for the main effect is presented in the last three columns: * p < 0.05, ** p < 0.01, ns = not significant.

	Vehicle		Mifepristone		MD	Treatment	Interaction
Volume (μl)	No MD	MD	No MD	MD
Cerebrum	1550.5 ± 10.0	1546.6 ± 11.9	1573.8 ± 16.1	1548.9 ± 15.7	ns	ns	ns
Corpus Callosum	30.4 ± 2.2	31.3 ± 2.4	31.0 ± 2.2	30.5 ± 3.0	ns	ns	ns
Lateral Ventricles	40.1 ± 1.8	38.6 ± 0.7	39.6 ± 1.1	38.9 ± 1.3	ns	ns	ns
Hippocampus	91.0 ± 1.1	91.4 ± 0.7	91.3 ± 1.2	90.6 ± 1.4	ns	ns	ns
Amygdala	29.2 ± 0.3	29.1 ± 0.3	29.4 ± 0.3	29.6 ± 0.5	ns	ns	ns
dmStriatum	16.8 ± 0.2	17.0 ± 0.3	17.6 ± 0.5	16.6 ± 0.3	ns	ns	ns
PFC	101.7 ± 0.4	99.6 ± 0.3	101.4 ± 1.0	98.9 ± 1.1	**	ns	ns
OFC	22.9 ± 0.2	22.1 ± 0.1	22.4 ± 0.3	22.2 ± 0.2	*	ns	ns
mPFC	14.4 ± 0.3	13.6 ± 0.2	14.1 ± 0.2	13.1 ± 0.3	**	ns	ns
Insular cortex	48.9 ± 0.3	48.5 ± 0.5	49.2 ± 0.7	48.9 ± 0.4	ns	ns	ns