Table 4. Mean diffusivity (10−3 mm2/s) and FA per ROI calculated from the DTI scan.
Data is expressed as mean ± SEM (n = 10 per group) and was analyzed using 2-way ANOVA with MD and mifepristone treatment as factors. Statistical significance of main effects is shown in the last three columns (ns = not significant).
| Vehicle | Mifepristone | |||
|---|---|---|---|---|
| No MD | MD | No MD | MD | |
| Mean Diffusivity | ||||
| Corpus Callosum | 0.20 ± 0.02 | 0.20 ± 0.01 | 0.20 ± 0.02 | 0.20 ± 0.01 |
| Hippocampus | 0.29 ± 0.01 | 0.29 ± 0.003 | 0.30 ± 0.01 | 0.29 ± 0.01 |
| Amygdala | 0.26 ± 0.01 | 0.26 ± 0.004 | 0.27 ± 0.01 | 0.26 ± 0.01 |
| dmStriatum | 0.26 ± 0.01 | 0.26 ± 0.004 | 0.26 ± 0.01 | 0.26 ± 0.01 |
| PFC | 0.25 ± 0.01 | 0.26 ± 0.01 | 0.26 ± 0.01 | 0.26 ± 0.01 |
| OFC | 0.24 ± 0.01 | 0.25 ± 0.01 | 0.24 ± 0.01 | 0.25 ± 0.01 |
| mPFC | 0.24 ± 0.01 | 0.25 ± 0.01 | 0.24 ± 0.01 | 0.25 ± 0.01 |
| Insular cortex | 0.24 ± 0.01 | 0.25 ± 0.01 | 0.25 ± 0.01 | 0.25 ± 0.01 |
| Mean FA | ||||
| Corpus Callosum | 0.52 ± 0.046 | 0.52 ± 0.012 | 0.52 ± 0.027 | 0.50 ± 0.045 |
| Hippocampus | 0.23 ± 0.004 | 0.24 ± 0.002 | 0.23 ± 0.002 | 0.23 ± 0.005 |
| Amygdala | 0.23 ± 0.007 | 0.22 ± 0.004 | 0.22 ± 0.005 | 0.22 ± 0.008 |
| dmStriatum | 0.18 ± 0.004 | 0.18 ± 0.002 | 0.18 ± 0.004 | 0.18 ± 0.005 |
| PFC | 0.20 ± 0.004 | 0.20 ± 0.003 | 0.19 ± 0.003 | 0.19 ± 0.005 |
| OFC | 0.20 ± 0.004 | 0.20 ± 0.003 | 0.20 ± 0.002 | 0.20 ± 0.005 |
| mPFC | 0.20 ± 0.005 | 0.20 ± 0.004 | 0.19 ± 0.004 | 0.19 ± 0.004 |
| Insular cortex | 0.20 ± 0.004 | 0.20 ± 0.003 | 0.19 ± 0.004 | 0.19 ± 0.006 |