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. 2017 Sep 25;12(9):e0185363. doi: 10.1371/journal.pone.0185363

Table 5. Reclassification of women with fracture in new models after adding cortical porosity or thickness to each of the original models including FRAX or Garvan alone.

Net reclassification improvement (NRI)
Event Nonevent Overall 95% CI p-value
FRAX + cortical porositya 0.204 -0.099 0.10 0.03, 0.18 0.005
FRAX + cortical thicknessa 0.175 -0.108 0.07 0.00, 0.14 0.060
Garvan + cortical porosityb 0.166 -0.112 0.05 -0.02, 0.12 0.131
Garvan + cortical thicknessb 0.137 -0.112 0.03 -0.04, 0.09 0.451

FRAX: Fracture Risk Assessment Tool for calculation of the 10-year probability of major fracture. Garvan: Fracture Risk estimate of the 10-year fracture risk for any fragility fracture.

aCompared with FRAX alone.

bCompared with Garvan alone.