Table 5. Reclassification of women with fracture in new models after adding cortical porosity or thickness to each of the original models including FRAX or Garvan alone.
Net reclassification improvement (NRI) | |||||
---|---|---|---|---|---|
Event | Nonevent | Overall | 95% CI | p-value | |
FRAX + cortical porositya | 0.204 | -0.099 | 0.10 | 0.03, 0.18 | 0.005 |
FRAX + cortical thicknessa | 0.175 | -0.108 | 0.07 | 0.00, 0.14 | 0.060 |
Garvan + cortical porosityb | 0.166 | -0.112 | 0.05 | -0.02, 0.12 | 0.131 |
Garvan + cortical thicknessb | 0.137 | -0.112 | 0.03 | -0.04, 0.09 | 0.451 |
FRAX: Fracture Risk Assessment Tool for calculation of the 10-year probability of major fracture. Garvan: Fracture Risk estimate of the 10-year fracture risk for any fragility fracture.
aCompared with FRAX alone.
bCompared with Garvan alone.