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. 2017 Sep 15;8(9):422–428. doi: 10.4239/wjd.v8.i9.422

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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Intraperitoneal insulin tolerance test and the expression of matrix metalloproteinase-11, collagen type VI alpha 3 and fibroblast-specific protein 1 in mice under different dietary conditions. A: IITT. Insulin tolerance was assessed in 12 h fasted mice, intraperitoneally injected with insulin (0.25 U/kg body weight). LFD (n = 6); HFD (n = 10). ^bP < 0.01 vs LFD; B: MMP-11, Col6α3 and FSP-1 mRNA expression in WAT of mice fed a low-fat (LFD) or high-fat (HFD) diet (n = 6 per each group). Results are the means ± SE of three independent measurements from each animal. ^dP < 0.001 vs LFD, for each group. MMP-11: Matrix metalloproteinase-11; IITT: Intraperitoneal insulin tolerance test; Col6α3: Collagen type VI alpha 3; FSP-1: Fibroblast-specific protein 1.