. Author manuscript; available in PMC: 2018 Sep 1.

Published in final edited form as: J Clin Lipidol. 2017 Jun 24;11(5):1289–1295. doi: 10.1016/j.jacl.2017.06.011

Table 3.

Omega-3 Index as predictor for change in lipid mediators.

Lipid Mediator^Ɨ	Odds Ratio^*	95% CI	P Value
EPA Products (n-3 PUFA mediators)
18-HEPE (n=39)	2.3	(1.7, 3.0)	<0.0001
15-HEPE (n=36)	1.7	(1.1, 2.9)	0.03
12-HEPE (n=37)	2.8	(0.7, 10.8)	0.13
5-HEPE (n=28)	1.9	(0.8, 1.5)	0.04
DHA Products (n-3 PUFA mediators)
10,17-diHDHA (n=36)	1.0	(0.7, 1.4)	0.95
4-HDHA (n=28)	3.6	(2.8, 4.8)	<0.0001
AA Products (n-6 PUFA mediators)
20-HETE (n=22)	0.9	(0.5, 1.5)	0.62
15-HETE (n=37)	0.6	(0.4, 1.0)	0.40
12-HETE (n=57)	1.3	(0.6, 1.1)	0.11
5-HETE (n=29)	0.7	(0.4, 1.4)	0.31

ORs calculated from regression models using GEE techniques. ORs are interpreted as follows: for each lipid mediator, the OR represents the percent increase when the omega-3 index is doubled.

^Ɨ

EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; AA, arachidonic acid; HEPE, hydroxyeicosapentaenoic acid; HDHA, hydroxydocosahexaenoic acid; HETE, hydroxyeicosatetraenoic acid.