Table 1.
Demographic and baseline clinical characteristics of HF patients prior to CF-LVAD implantation
| Characteristics | Pre-implant HF patients (n = 31) | |
|---|---|---|
|
| ||
| Non-bleeder group (n = 19) | Bleeder group (n =12) | |
| Demography | ||
| Age in years, median (IQR) | 61 (48 – 76) | 60.0 (25 – 70) |
| Sex, n (% male) | 18 (94.7 %) | 9 (75.0 %) |
| Race | ||
| Caucasian white, n (%) | 11 (57.9 %) | 4 (33.3 %) |
| Black, n (%) | 8 (42.1 %) | 8 (66.7 %) |
| Height in meter, median (IQR) | 1.8 (1.7 – 1.9) | 1.7 (1.6 – 1.9) |
| Weight in kilograms, median (IQR) | 102 (60 – 127.9) | 80.0 (53.0 – 112.0)* |
| Body mass index (BMI) (kg/m2), median (IQR) | 31.0 (20.8 – 39.0) | 24.8 (19.5 – 34.3)* |
| Body surface area (BSA) (m2), median (IQR) | 2.3 (1.7 – 2.5) | 1.9 (1.6 – 2.4)* |
| History of smoking, n (%) | 5 (26.3 %) | 3 (25.0 %) |
| History of substance abuse | ||
| Ethyl alcohol abuse, n (%) | 3 (15.8 %) | 2 (16.7 %) |
| Drug abuse, n (%) | 5 (26.3 %) | 2 (16.7 %) |
| Vital signs | ||
| Systolic blood pressure (mmHg), mean ± SD | 97.4 ± 11.6 | 112.25 ± 14.7 |
| Diastolic blood pressure (mmHg), mean ± SD | 58.0 ± 7.2 | 74.5 ± 20.6 |
| Etiology of heart disease | ||
| Ischemic cardiomyopathy, n (%) | 8 (42.1 %) | 4 (33.3 %) |
| Non-ischemic cardiomyopathy, n (%) | 8 (42.1 %) | 4 (33.3 %) |
| Idiopathic Cardiomyopathy, n (%) | 3 (15.8 %) | 4 (33.3 %) |
| Echocardiographic parameters | ||
| Left ventricular end diastolic diameter (mm), mean ± SD | 67.7 ± 9.2 | 69.6.5 ±10.7 |
| Left ventricular ejection fraction, (%), mean ± SD | 13.8 ± 3.8 | 16.2 ± 5.8 |
Demographic and clinical parameters of non-bleeder versus bleeder groups of HF patients were statistically compared by Mann-Whitney ‘U’ test (for median values with IQR), χ2-test (for results presented as percentages) and Student’s t-test (for results presented as mean±SD) as applicable,
*
p<0.05 were considered significant.