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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Exp Neurol. 2017 Jul 28;297:82–91. doi: 10.1016/j.expneurol.2017.07.016

Figure 1.

Figure 1

LPS dose titration studies. IP administration of 50 μg/kg LPS yielded undetectable plasma endotoxin (A) and no changes in granulocyte count (B), core temperature (C), or weight (D), while effects were seen with 4 mg/kg and 20 mg/kg. (D) Elevated IL-6 was seen in all mice after 6 hours and remained elevated at 24 hours in mice receiving 20 mg/kg LPS. Values represent means ± SD (n = 3). 1-way ANOVA: * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.