Table 4.
Association of Risk Gradient with Primary and Coronary Endpoints
| Risk Gradient | Event Number (%) |
HR1 (95%CI), p- value2 |
|
|---|---|---|---|
| Primary Endpoint | DM−, MS− | 80 (14.0%) | Referent, 0.0018 |
| DM−, MS+ | 246 (14.7%) | 1.049 (0.815, 1.350) | |
| DM+, MS+/MS− | 225 (19.5%) | 1.411 (1.093, 1.823) | |
| DM+, MS+/MS− vs DM−, MS+/MS− | 1.226 (1.083, 1.388) | ||
| ---, 0.0013 | |||
| Coronary Events | DM−, MS− | 70 (12.2%) | Referent, 0.0005 |
| DM−, MS+ | 226 (13.5%) | 1.108 (0.847, 1.448) | |
| DM+, MS+/MS− | 210 (18.2%) | 1.527 (1.164, 2.004) | |
| DM+, MS+/MS− vs DM−, MS+/MS− | 1.273 (1.118, 1.450) | ||
| ---, 0.0003 |
DM = history of diabetes at baseline, negative (−) or positive (+)
MS = metabolic syndrome at baseline, negative (−) or positive (+)
1
Cox regression models adjusted for sex, age and the number of criteria met as categorical term. Hazard ratio comparing to DM−, MS− as referent
2
p-value based on Wald test
3
Coronary events consist of death from coronary artery disease, myocardial infarction, hospitalization for acute coronary syndrome and coronary revascularization