Fig. 5.
DNA vaccines PV-1947D (3hα-Syn85–99-MultiTEP; A), PV-1948D (3hα-Syn109–126-MultiTEP; B), PV-1949D (3hα-Syn126–140-MultiTEP; C), and PV-1950D (3hα-Syn126–140-3hα-Syn109–126-3hα-Syn85–99-MultiTEP; D) induced high titers of antibodies specific to appropriate peptide/s. Endpoint titers of antibodies specific to hα-Syn85–99, hα-Syn109–126, hα-Syn126–140 peptides were detected in sera collected after the third immunization with indicated vaccines by ELISA. Lines indicate the mean values of antibody titers (**P<0.01, ****P<0.0001).