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. 2017 Sep 25;8:695. doi: 10.1038/s41467-017-00795-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Expression of MOB1(wt) or MOB1(K104E/K105E), but not MOB1(D63V) or MOB1(D63V/K104E/K105E), fully suppresses the mats eye overgrowth phenotype. Shown are frontal views of eyes from female progeny of the indicated genotypes (wt, wild-type; DV D63V, KEKE K104E/K105E, DVKEKE D63V/K104E/K105E). A wild-type control eye is shown for comparison a. Expression of MOB1(wt) b or MOB1(K104E/K105E) d fully suppress the severe tissue overgrowth upon eyeless-FLP (ey-FLP) mediated formation of mats mutant clones in the eye (compare b, d with a and f). Expression of MOB1(D63V) c or MOB1(D63V/K104E/K105E) e does not fully suppress eye overgrowth upon mats loss-of-function (compare c, e with a and f)