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. 2017 Sep 25;7:12232. doi: 10.1038/s41598-017-12001-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Viral titre versus stratified age groups during the 2014–2015 and 2015–2016 seasons in Alberta Canada. (a) 2014–2015 RSV type-A and B viral loads versus age stratification. RNA was extracted from patient nasopharyngeal samples, and RSV was quantified by qRT-PCR. The RSV RNA copies per mL were determined by comparison to a known viral quantitative RT-PCR standard. (b) 2015–2016 RSV type-A and RSV type-B viral loads versus age stratification. (c) Combined 2014–2016 RSV type-A and B viral loads versus age stratification. Horizontal lines represent the median of the data. (d) Summary of a systematic meta-analysis of clinical studies examining RSV type-B prevalence in those under 1 year of age. *Only stratified those less than 2 years of age or no age stratification reported. The dotted line indicates the summary mean of RSV type-B prevalence among the studies.