Table 1.
Up and down regulated pathway enrichment by KEGG.
| Rank | MapID | MapTitle | Pvalue | AdjustedPv |
|---|---|---|---|---|
| Down regulated pathway from D0 to D7 enrichment by KEGG | ||||
| 1 | map03010 | Ribosome | 3.20E-31 | 5.70E-29 |
| 2 | map03040 | Spliceosome | 1.71E-16 | 1.52E-14 |
| 3 | map03030 | DNA replication | 6.09E-13 | 3.61E-11 |
| 4 | map03013 | RNA transport | 6.96E-12 | 2.38E-10 |
| 5 | map04110 | Cell cycle | 8.01E-12 | 2.38E-10 |
| Up regulated pathway from D0 to D7 enrichment by KEGG | ||||
| 1 | map04010 | MAPK signaling pathway | 2.18E-16 | 3.40E-14 |
| 2 | map04020 | Calcium signaling pathway | 7.22E-15 | 3.75E-13 |
| 3 | map04070 | Phosphatidylinositolsignaling system | 4.67E-13 | 1.21E-11 |
| 4 | map04080 | Neuroactive ligand-receptor interaction | 4.99E-08 | 8.66E-07 |
| 5 | map04144 | Endocytosis | 3.83E-06 | 5.44E-05 |
| 6 | map04012 | ErbB signaling pathway | 9.47E-06 | 0.000123 |
| 7 | map00562 | Inositol phosphate metabolism | 4.56E-05 | 0.000508 |
| 8 | map04310 | Wnt signaling pathway | 0.000168 | 0.001751 |
| Down regulated pathway from D7 to D28 enrichment by KEGG | ||||
| 1 | map04080 | Neuroactive ligand-receptor interaction | 0.00396 | 0.17822223 |
| 2 | map00514 | O-Mannosyl glycan biosynthesis | 0.010899 | 0.18965783 |
| 3 | map04020 | Calcium signaling pathway | 0.012644 | 0.18965783 |
| 4 | map04310 | Wnt signaling pathway | 0.035705 | 0.362217316 |
| Up regulated pathway from D7 to D28 enrichment by KEGG | ||||
| 1 | map04510 | Focal adhesion | 7.19E-20 | 7.76E-18 |
| 2 | map04512 | ECM-receptor interaction | 9.55E-13 | 5.16E-11 |
| 3 | map04610 | Complement and coagulation cascades | 0.00025 | 0.004491 |
| 4 | map04350 | TGF-beta signaling pathway | 0.001724 | 0.023275 |
| 5 | map04810 | Regulation of actin cytoskeleton | 0.013427 | 0.145012 |
| 6 | map04340 | Hedgehog signaling pathway | 0.017364 | 0.170483 |
| 7 | map04115 | p53 signaling pathway | 0.026175 | 0.22296 |
| 8 | map04310 | Wnt signaling pathway | 0.026838 | 0.22296 |