Table 4.
Effects of age. All tables show data thresholded at 0.001 uncorrected, only clusters with>20 voxels are shown.
| A | ||||||
|---|---|---|---|---|---|---|
| Anatomical area (peak coordinate) | MNI coords mm (x, y, z) | cluster | peak | peak | peak | peak |
| MRIcron (automated anatomical labeling) | equivk | p(FWE-corr) | T | equivZ | p(unc) | |
| Angular (L) | −48, −74, 30 | 2857 | <0.001 | 6.4 | 5.98 | <0.001 |
| Middle occipital (L) | −40, −78, 36 | 0.001 | 5.8 | 5.48 | <0.001 | |
| Angular (L) | −40, −62, 32 | 0.143 | 4.33 | 4.19 | <0.001 | |
| Calcarine (L) | −2, −87, 14 | 9176 | 0.005 | 5.27 | 5.02 | <0.001 |
| Cuneus (L) | −10, −93, 14 | 0.007 | 5.18 | 4.94 | <0.001 | |
| Calcarine (L) | −2, −63, 16 | 0.017 | 4.95 | 4.74 | <0.001 | |
| Angular (R) | 48, −69, 32 | 589 | 0.025 | 4.84 | 4.65 | <0.001 |
| Superior frontal (R) | 30, 27, 52 | 860 | 0.028 | 4.81 | 4.62 | <0.001 |
| Middle frontal (R) | 26, 42, 42 | 0.327 | 4.04 | 3.92 | <0.001 | |
| Middle temporal (L) | −56, −48, −6 | 1025 | 0.078 | 4.52 | 4.36 | <0.001 |
| Middle temporal (L) | −51, −42, 0 | 0.672 | 3.7 | 3.6 | <0.001 | |
| Middle temporal (L) | −56, −36, 10 | 0.891 | 3.44 | 3.37 | <0.001 | |
| Middle frontal (L) | −27, 38, 45 | 250 | 0.256 | 4.13 | 4.01 | <0.001 |
| Superior frontal (L) | −21, 44, 44 | 0.745 | 3.62 | 3.53 | <0.001 | |
| Superior frontal (L) | −22, 36, 36 | 0.958 | 3.3 | 3.23 | 0.001 | |
| Superior temporal (R) | 64, −9, 8 | 311 | 0.457 | 3.9 | 3.79 | <0.001 |
| Rolandic operculum (R) | 51, −8, 20 | 0.957 | 3.3 | 3.23 | 0.001 | |
| Postcentral (R) | 64, −6, 27 | 254 | 0.644 | 3.72 | 3.63 | <0.001 |
| Precentral (R) | 20, −22, 66 | 54 | 0.653 | 3.71 | 3.62 | <0.001 |
| Precentral (R) | 30, −22, 64 | 0.939 | 3.35 | 3.28 | 0.001 | |
| Medial frontal orbital (R) | 2, 54, −8 | 111 | 0.676 | 3.69 | 3.6 | <0.001 |
| Cerebelum (R) | 12, −54, −8 | 134 | 0.707 | 3.66 | 3.57 | <0.001 |
| Precentral (R) | 45, −10, 52 | 193 | 0.715 | 3.65 | 3.56 | <0.001 |
| Parahippocampal (L) | −20, −38, −8 | 194 | 0.717 | 3.65 | 3.56 | <0.001 |
| Parahippocampal (L) | −27, −36, −10 | 0.791 | 3.57 | 3.49 | <0.001 | |
| Superior temporal (L) | −54, −15, 2 | 26 | 0.732 | 3.64 | 3.55 | <0.001 |
| Superior temporal (R) | 46, −32, 15 | 77 | 0.784 | 3.58 | 3.5 | <0.001 |
| Superior temporal (R) | 57, −2, −8 | 23 | 0.869 | 3.48 | 3.4 | <0.001 |
| Precentral (R) | 39, −15, 38 | 28 | 0.966 | 3.28 | 3.21 | 0.001 |
| Precentral (R) | 36, −15, 48 | 0.989 | 3.16 | 3.1 | 0.001 | |
| B | ||||||
| Anatomical area (peak coordinate) | MNI coords mm (x, y, z) | cluster | peak | peak | peak | peak |
| MRIcron (automated anatomical labeling) | equivk | p(FWE-corr) | T | equivZ | p(unc) | |
| Anterior cingulate cortex (R) | 9, 24, 26 | 122 | 0.334 | 4.15 | 4.03 | <0.001 |
| Postcentral (L) | −39, 22, 50 | 98 | 0.604 | 3.89 | 3.78 | <0.001 |
| Postcentral (L) | −51, −26, 57 | 25 | 0.984 | 3.34 | 3.27 | 0.001 |
| C | ||||||
| Anatomical area (peak coordinate) | MNI coords mm (x, y, z) | cluster | peak | peak | peak | peak |
| MRIcron (automated anatomical labeling) | equivk | p(FWE-corr) | T | equivZ | p(unc) | |
| Fusiform (L) | −24, −75, −10 | 15740 | <0.001 | 7.93 | 7.19 | <0.001 |
| Fusiform (L) | −28, −60, −10 | <0.001 | 7.56 | 6.9 | <0.001 | |
| Fusiform (R) | 28, −66, −9 | <0.001 | 7.28 | 6.69 | <0.001 | |
| Precentral (R) | 58, 2, 40 | 311 | 0.081 | 4.62 | 4.45 | <0.001 |
| Precentral (R) | 63, 9, 26 | 0.933 | 3.51 | 3.43 | <0.001 | |
| Superior occipital (R) | 24, −81, 40 | 348 | 0.083 | 4.61 | 4.44 | <0.001 |
| Superior occipital (R) | 32, −76, 45 | 0.871 | 3.61 | 3.53 | <0.001 | |
| Superior parietal (R) | 34, −45, 62 | 1463 | 0.116 | 4.51 | 4.35 | <0.001 |
| Inferior parietal (R) | 28, −48, 54 | 0.183 | 4.37 | 4.22 | <0.001 | |
| Postcentral (R) | 32, −33, 51 | 0.802 | 3.7 | 3.6 | <0.001 | |
| Middle frontal (R) | 44, −3, 54 | 817 | 0.12 | 4.5 | 4.34 | <0.001 |
| Precentral (R) | 34, −2, 50 | 0.334 | 4.15 | 4.03 | <0.001 | |
| Superior frontal (R) | 32, −4. 62 | 0.693 | 3.81 | 3.71 | <0.001 | |
| Postcentral (L) | −62, −15, 30 | 799 | 0.282 | 4.22 | 4.08 | <0.001 |
| Supramarginal (L) | −58, −26, 26 | 0.298 | 4.2 | 4.07 | <0.001 | |
| Postcentral (L) | −51, −22, 33 | 0.903 | 3.57 | 3.48 | <0.001 | |
| Calcarine (R) | 21, −54, 10 | 360 | 0.304 | 4.19 | 4.06 | <0.001 |
| Lingual (R) | 6, −60, 9 | 0.955 | 3.46 | 3.38 | <0.001 | |
| NA | 9, −27, −4 | 472 | 0.479 | 4 | 3.89 | <0.001 |
| NA | −3, −45, 8 | 0.857 | 3.63 | 3.54 | <0.001 | |
| NA | −6, −28, −8 | 0.906 | 3.56 | 3.48 | <0.001 | |
| Superior parietal (L) | −33, −57, 63 | 39 | 0.707 | 3.79 | 3.69 | <0.001 |
| Inferior parietal (L) | −34, −40, 48 | 63 | 0.806 | 3.69 | 3.6 | <0.001 |
| NA | 24, −26, −4 | 32 | 0.852 | 3.64 | 3.55 | <0.001 |
| Inferior frontal operculum (L) | −44, 6, 30 | 248 | 0.866 | 3.62 | 3.53 | <0.001 |
| Precentral (L) | −50, 3, 34 | 0.868 | 3.62 | 3.53 | <0.001 | |
| Postcentral (R) | 66, −12, 22 | 31 | 0.884 | 3.59 | 3.51 | <0.001 |
| Inferior frontal operculum (L) | −52, 9, 20 | 109 | 0.914 | 3.55 | 3.46 | <0.001 |
| Precentral (L) | −44, −3, 58 | 75 | 0.932 | 3.51 | 3.43 | <0.001 |
| Precentral (L) | −40, −4, 51 | 0.975 | 3.39 | 3.32 | <0.001 | |
| Superior temporal (L) | −46, −8, −6 | 36 | 0.95 | 3.47 | 3.39 | <0.001 |
| Middle cingulate cortex (R) | 12, −20, 44 | 25 | 0.961 | 3.44 | 3.36 | <0.001 |
| Postcentral (R) | 60, −12, 40 | 86 | 0.967 | 3.42 | 3.35 | <0.001 |
| Posterior cingulate cortex (L) | −8, −36, 34 | 26 | 0.971 | 3.41 | 3.33 | <0.001 |
| Middle frontal (R) | 33, 38, 40 | 30 | 0.979 | 3.37 | 3.3 | <0.001 |
Anatomic labels are shown for peak coordinates and were defined using the automatic anatomic labelling in MRIcron. A. The contrast older>young for pain>no pain, B. The contrast young>older for pain>baseline. C. The contrast older>young for pain>baseline.