Table 2.
Studies for predictive scores related to outcomes of rhythm control or arrhythmia progression in patients with atrial fibrillation
| First author, year | Scores (points) | Enrolled patients (n) | pAF (%) | CA protocol | AFLAT-Free (%) | Procedure times | FU (months) | C Index/AUC | Predictive value | CHADS2/CHA2DS2–VASc compared |
|---|---|---|---|---|---|---|---|---|---|---|
| Tang [21], 2012 |
HATCH (0–7) | 488 | 100 | CPVI | 63.93 | Single | 27.4 ± 17.7 | Not measured | No | Not compared |
| Maciej [23], 2013 |
ALARMEc (0–5) | 213 | 47 | Stepwise* | 90 | Repeated | 24 | 0.657 vs. 0.533/0.519 | Yes | Worse |
| Ugur [25] 2013 |
BASE-AF2 (0–6) | 236 | 79.6 | Cryoablation | 74.5 | Single | 20 | 0.94 (score ≥3) | Yes | Not compared |
| Letsas [31] 2014 | CHADS2 (0–6)/CHA2DS2–VASc (0–9) | 126 | 100 | CPVI | 70.6 | Single | 16 | 0.644/0.627 (score ≥2) | Yes | – |
| Kornej [26], 2015 | APPLE (0–5) | 261 | 48 | Stepwise* | 38.3 | Single | ≥12 | 0.634 vs. 0.538/0.542 | Yes | Worse |
| Roger [28], 2016 | CAAP-AF (0–13) | 937 | 31.6 | Stepwise* | 79.1 | Repeated | 21.6 ± 1.6a | 0.650 | Yes | Not compared |
| Mujovic [29], 2017 | MB-LATER (0–6) | 133 | 69.2 | Stepwise* | 85 | Repeated | 29 ± 10.1 | 0.782 vs. 0.552/0.519 | Yes | Worse |
AFLAT atrial flutter or atrial tachycardia, AUC area under curve, CPVI circumferential pulmonary vein isolation, FU follow-up, pAF paroxysmal atrial fibrillation
* Stepwise, necessary additional linear lesion, or complex fractionated atrial electrogram-guided ablation after CPVI