Table 1.
Overall effect sizes and Egger’s bias coefficients
Marker | Number of studies included | Effect size | Heterogeneity | Publication bias | |||
---|---|---|---|---|---|---|---|
Odd’s ratio | 95% CI | I 2 (%) | p-value | Egger’s bias coefficient | p-value | ||
PSD | |||||||
Laterality | 60a | 1.07 | 0.93–1.23 | 49.6 | < .001 | 0.14 | .743 |
Type | 14b | 0.94 | 0.65–1.36 | 33.3 | .102 | −0.06 | .943 |
Frontal lesions | 30c | 1.54 | 1.27–1.88 | 43.4 | .004 | 0.92 | .132 |
Subcortical lesions | 10d | 1.06 | 0.81–1.38 | 0.0 | .601 | 1.00 | .186 |
Basal ganglia lesions | 12e | 1.78 | 1.20–2.66 | 65.3 | .001 | 0.24 | .884 |
PSA | |||||||
Laterality | 9 | 1.16 | 0.62–2.18 | 63.5 | .005 | 1.69 | .262 |
Type | 4 | 0.82 | 0.19–3.53 | 75.2 | .007 | −3.92 | .273 |
Frontal lesions | 5 | 0.84 | 0.44–1.59 | 0.0 | .635 | 2.71 | .055 |
Subcortical lesions | 2 | 1.03 | 0.38–2.80 | 0.0 | .686 | Not enough data | |
Basal ganglia lesions | 4 | 1.32 | 0.79–2.21 | 0.0 | .891 | −0.42 | .536 |
CI confidence interval, PSA post-stroke apathy, PSD post-stroke depression
aSix of the 60 studies provided data on more than one time point
bOne of the 14 studies provided data on more than one time point
cFive of the 30 studies provided data on more than one time point
dTwo of the 10 studies provided data on more than one time point
eOne of the 12 studies provided data on more than one time point