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. 2017 Sep 1;77(15):1623–1643. doi: 10.1007/s40265-017-0804-3

Table 6.

Profile of adverse effects for selected antipsychotics at therapeutic doses (derived from Procyshyn et al. [92])

Drug Sedationa Hypotension/dizzinessb Extrapyramidal side effectsc Anticholinergic effectsd
Haloperidol + + +++ +
Levomepromazine (methotrimeprazine) +++ +++ ++ +++
Chlorpromazine +++ +++ ++ +++
Olanzapine +++ + + ++
Quetiapine +++ ++ + +++
Risperidone ++ ++ ++ +
Aripiprazole ++ + + +

+ indicates frequency >2%, ++ indicates frequency >10%, +++ indicates frequency >30%, ↓ indicates decreased, ↑ indicates increased

aDue to antihistaminic effect of certain antipsychotics

bHypotension/dizziness: due to adrenergic side effects

cSee text for details

dPeripheral: blurred vision, dry mouth, constipation, ↓ bronchial secretion, ↓ sweating, difficulty urination, urinary retention, tachycardia; central: impairment of concentration and memory, ↑ confusion (delirium)