Figure 3.

Sphingolipid enzymes regulate neuromuscular function. (A–E) Age-dependent changes in paralysis response of 3-day and 7 day old wild type animals to aldicarb (1 mM) exposure in the indicated strains. (F) Percent of animals paralyzed for the indicated strains after 90-min of aldicarb exposure. For all experiments, animals were examined 3 or 7 days post-hatching, and were transferred onto NGM plates containing aldicarb for testing. For all, error bars are ± SEM and are performed in triplicates; ^*p < 0.01 and ^**p < 0.001 for comparisons to the wild type counterpart and #p < 0.01 for comparisons to the 3 day old counterpart.