Table 2.

Life history traits of sphingolipid metabolic enzyme mutants.

	Lifespan (days)∧ number (censored animals) and trials indicated	Brood size (surviving progeny)	Development (48 h)		Development (72 h)
			Body length (μm)	Percent adult (YA+A)	Body length (μm)	Percent adult (YA+A)
wild type (N2)	20.1 ± 0.4 n = 90 (2), 4 trials	267.0 ± 18.6 n = 7	756.4 ± 11.5 n = 134	31.3 n = 303	1162.9 ± 12.5 n = 114	100 n = 386
sphk-1 (ok1097)/ SPH kinase	13.6 ± 0.4**n = 111 (3), 6 trials	88.2 ± 13.5**n = 5	666.9 ± 9.9*n = 38	9.2 n = 153	885.6 ± 12.3**n = 38	95.3 n = 191
hyl-1(gk203)/ CER synthase	16.13 ± 0.4**n = 100 (6), 4 trials	291.4 ± 28.0 n = 5	996.2 ± 13.4**n = 50	18.3 n = 104	1195.9 ± 12.2 n = 50	94 n = 116
hyl-2(gnv1)/ CER synthase	17.7 ± 0.6**n = 73 (2), 3 trials	248.5 ± 30.0 n = 10	792.3 ± 17.6 n = 90	2.6 n = 116	1152.2 ± 11.7 n = 86	89.1 n = 55
sphk-1; hyl-1	12.4 ± 0.4**n = 65 (6), 4 trials	104.4 ± 9.5**n = 5	662.7 ± 11.7**n = 41	0 n = 79	851.6 ± 14.1** n = 58	78.9 n = 142
sphk-1; hyl-2	7.1 ± 0.7**n = 20 (0), 2 trials	9.7 ± 4.5**n = 8	647.9 ± 19.3** n = 28	n/a	778.7 ± 26.1** n = 27	n/a
cerk-1(ok1252)/ CER kinase	19.9 ± 0.3 n = 127 (2), 4 trials	244.7 ± 24.2 n = 9	760.7 ± 10.3 n = 84	34.1 n = 225	1045.9 ± 8.8**n = 32	100.0 n = 171

^∧p-values determined by a Kaplan-Meier test and Bonferroni correction with the program OASIS (Yang et al., 2011).

^*p < 0.01 and

^**p < 0.001, ANOVA and Tukey HSD compared to wild type and (± SEM for all data).