Fig. 1.

Inhibition of IL-6-induced COX-2 expression in THP1 cells. PMA-differentiated THP1 cells were pre-treated with kaempferol (Kae) at various concentrations followed by induction with IL-6 for 2 h. Expression of COX-2 mRNA and protein were studied using semi-quantitative PCR (A) and western blot using anti-COX-2 monoclonal antibody (Clone D5H5) (B). The band intensities were quantitated and represented as mean ± SEM of three independent experiments.