Table 1B.
: Genes up-regulated by ECM grouped according to functional pathways.
| MID_ NH versus LATE_NH | Regulated genes |
|---|---|
| Jak-STAT signaling pathway | IL6, CytokineR, PI3K, CycD |
| Cytokine-cytokine receptor interaction | IL6, IL11, LIF, BSF3, CSF3, GHR, CSF2RB, SF11B, SF21, IL1R2, HGF, FLT, IL18 |
| Complement and coagulation cascades | F3, THBD, serpinE1 |
| Hematopoietic cell lineage | G-SCF, IL−6, IL−11,CD121 |
| TGF-beta signaling pathway | THBS1, BMP, FST, Smad1/5/8 |
| Cell cycle | Bub1, BubR1, cd20, cyclinB, Plk1, cyclinD, MCM5 |
| oocyte meiosis | IGF−1, Bub1, PI3K, cdc20, Plk1, CycB1, AC |
| Neurotrophin signaling pathway | TrkC, PI3K, IkB, PKCδ, RIMID, IRAK |
| Wnt signaling pathway | FRP, Wnt, Frizzled, Nkd, NFAT |
| MID_H versus LATE_H | Regulated genes |
| Jak-STAT signaling pathway | IL6, CytokineR, PI3K, CyclinD |
| Cytokine-cytokine receptor interaction | IL6, IL11, LIF, BSF3, CSF3, GHR, CSF2RB, SF11B, SF21, IL1R2 |
| Complement and coagulation cascades | F3, THBD, serpinE1, PLAU, DF |
| Hematopoietic cell lineage | G-SCF, IL−6, IL−11,CD121 |
| TGF-beta signaling pathway | Smad2,3, THBS1, BMP, FST, Smad1/5/8 |
| p53 signaling pathway | CyclinD, CyclinB, IGF, PAI, p53R2 |
| Cell cycle | Bub1, BubR1, Smad2,3, cd20, cyclinB, Plk1, cyclinD, |
| Oocyte meiosis | IGF−1, Bub1, PI3K, cdc20, Plk1, CycB1, AC |
| Neurotrophin signaling pathway | TrkC, PI3K, IkB |
| NOD-like receptor signaling pathway | RIMID, IkB, IL−6 |
| Wnt signaling pathway | FRP, Wnt, Frizzled, Nkd, Smad3, NFAT, fra1, CycD, uterine |
| Galactose metabolism | Glucose phosphomutase, Glucose−1-phosphate, Hexokinase, uridylyltransferase UDP-galactose 4-epimerase |