Fig. 1.

An increased feces score was found after each DSS treatment, while bodyweight loss was only found after acute DSS treatment. A) The bodyweight changes of control and DSS-treated mice during repeated DSS treatment are illustrated in the figure. B) The increased fecal scores of DSS-treated mice as compared to control mice after the first DSS treatment until end of the experiment are shown (n = 18 during cycle 1 DSS treatment, n = 12 during cycle 2 DSS-treatment and n = 6 cycle 3 DSS treatment). C) The colon length (cm) /weight (mg) ratio was determined (n = 6 per group). All results are expressed as + SEM, * indicates significant different between control and DSS-treated group. # Indicates significant different between the DSS-treatment cycles ^{##, **} P < 0.01, ^*** P < 0.001.