Table 3.
Comparison of pretreatment and post-treatment clinical parameters between the amitriptyline and pregabalin groups
| Parameters | Pre-treatment | Post-treatment | ||||
|---|---|---|---|---|---|---|
| Amitiriptyline (n=35) | Pregabalin (n=36) | p | Amitiriptyline (n=32) | Pregabalin (n=34) | p | |
| VAS | 7.42±1.67 | 8.04±1.44 | * | 4.26±1.93 | 4.27±1.83 | * |
| NHP-pain | 66.22±26.29 | 72.70±21.14 | * | 24.64±15.46 | 30.20±15.85 | * |
| FIQ-pain | 7.72±1.71 | 7.91±1.65 | * | 3.56±1.82 | 4.50±1.80 | 0.04 |
| MFIS-pf | 21.22±6.66 | 21.80±6.54 | * | 14.62±4.46 | 14.32±5.043 | * |
| NHP-fatigue | 91.86±23.68 | 78.37±35.32 | * | 33.55±37.92 | 34.44±38.21 | * |
| FIQ-fatigue | 8.41±1.62 | 8.3333±1.72 | * | 3.9375±1.79 | 4.14±1.64 | * |
| NHP-pa | 34.51±28.18 | 38.57±25.59 | * | 8.55±14.18 | 16.53±20.51 | * |
| HADS-depression | 8.94±2.90 | 8.36±2.63 | * | 6.94±1.96 | 7.02±2.08 | * |
| HADS-anxiety | 10.17±2.06 | 9.41±1.93 | * | 8.20±1.90 | 7.26±1.60 | 0.031 |
| MMSE | 24.82±3.15 | 25.44±2.96 | * | 25.56±3.25 | 26.32±2.55 | * |
*
p>0.05.
FIQ: Fibromyalgia Impact Questionnaire; FSS: Fatigue Severity Scale; HADS: Hospital Anxiety and Depression Scale; MFIS: Modified Fatigue Impact Scale; MMSE: Mini Mental State Examination; NHP: Nottingham Health Profile; pa: Physical activity; pf: Physical function; VAS: Visual Analogue Scale.