. Author manuscript; available in PMC: 2017 Sep 26.

Published in final edited form as: J Neuroimaging. 2015 Feb 6;25(5):799–806. doi: 10.1111/jon.12193

Table 1.

Demographic, Clinical and Imaging Characteristics of the Study Cohort

	Patients (n = 15)	Healthy Volunteers (n = 10)	P-Value
Age	44.8 ± 8.8 (28–57)	44.3 ± 11.1 (22–57)	.9^*
Sex (female/male)	7/8	6/4	.5^**
Years of MS	11.3 ± 10.1 (.3–33)	N/A	N/A
MS type (RR/SP)	13/2	N/A	N/A
EDSS	1.5 (0–6.0)	N/A	N/A
T₂-LV (cm³)	8.9 ± 13.1 (0–42.5)	N/A	N/A
cBH-LV (cm³)	3.9 ± 6.3 (0–18.4)	N/A	N/A
CSF-TSI-LV (cm³)	1.2 ± 2.6 (0–7.3)	N/A	N/A
BPF	.74 ±.05 (.67–.83)	N/A	N/A

Data related to continuous variables are expressed in mean ± SD (minimum-maximum value), but for the expanded disability stats scale (EDSS) score for which median (minimum-maximum values) are provided; N/A = not applicable;

by unpaired t-test;

^**

by x-² test.

RR = relapsing remitting; SP = secondary progressive; T₂-LV = volume of hyperintense lesions in T₂-w image; cBH-LV = chronic black holes lesion volume; CSF-TSI-LV = volume of hyperintense lesions in cerebrospinal fluid tissue-specific imaging; BPF = brain parenchyma fraction.