Table 1.
Frequency of adipogenesis related transcription factor binding sitesa in 14-3-3 genes promoter regions.
| 14-3-3β | 14-3-3γ | 14-3-3ε | 14-3-3η | 14-3-3θ | 14-3-3ζ | 14-3-3σ | |
| C/EBP α | 0 | 4 | 0 | 0 | 0 | 1 | 0 |
| C/EBPβ | 2 | 1 | 0 | 1 | 1 | 0 | 0 |
| C/EBPδ | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
| CREB | 0 | 4 | 0 | 1 | 1 | 1 | 0 |
| GATA2 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
| GATA3 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
| GR | 0 | 0 | 0 | 0 | 0 | 2 | 0 |
| KROX | 0 | 2 | 6 | 0 | 0 | 1 | 0 |
| PPARγ | 1 | 2 | 1 | 0 | 0 | 0 | 0 |
| SMAD | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
| STAT5A | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
| Total | 5 | 17 | 10 | 5 | 3 | 7 | 0 |
a
The sequences (strictly conserved nucleotides in capital letters, less conserved in lower case letters) of the transcriptions factors are as follows: C/EBPα, ccaTTgcttaatct; C/EBPβ, TTTAGCAA; C/EBPδ ATTGCTTAA; CREB, TGACACCA/TGAAGTC; GATA2, GATCAGA; GATA3, GATCAAA; GR, TGTTC; KROX, CTCCCCC; PPARGγ, TGGCCTTTGCCC; SMAD, AGACagctc; STAT5A, TTCCTTGAACACCACTGCTTTG. The locations of these sequences on 14-3-3 genes are given in Table S2 (Supplementary material).