Table 1.

Clinical and angiographic characteristics in patients with change of normal segment ECV per-patient between acute and follow-up scan

	Normal segment ECV ↓ (n = 22)		Normal segment ECV ↑ (n = 28)
	Mean/Median/Count	SD/ 25%–75%/%	Mean/Median/Count	SD/25%–75%/%	p-value
Patient Demographics
Age, yrs	60	11	58	11	0.39
Sex (Male)c	20	40	22	44	0.24
Smokerc	14	28	16	32	0.65
Hypertensionc	5	10	3	6	0.25
Hyperlipidaemiac	9	18	8	16	0.37
Diabetes Mellitusc	4	8	2	4	0.24
Strokec	1	2	0	0	0.26
Presenting Characteristics
Systolic Blood Pressure, mmHg	137	24	134	36	0.88
Heart rate, beats/min	73	14	74	16	0.95
Time from onset of CP to reperfusion, minc	261	158–454	222	149–344	0.43
Heart Failure Killip Classa
Ic	20	40	26	52	0.80
IIc	1	2	2	4	0.70
III-IVc	1	2	0	0	0.26
Ventricular fibrillation at presentationc	0	0	3	6	0.11
Angiographic Characteristics
Number of diseased arteriesb
Single vessel diseasec	16	30	16	32	0.26
Two vessel diseasec	5	10	5	10	0.67
Three vessel diseasec	1	2	7	14	0.05
Culprit Vessel
Left main stemc	0	0	1	2	0.37
Left anterior descendingc	14	28	15	30	0.48
Left circumflexc	2	4	2	4	0.80
Right coronaryc	6	12	11	22	0.38
QRS duration, msecc	90	86–110	94	82–100	0.86
TIMI coronary flow pre-PCI (<2)c	18	36	26	52	0.15
TIMI coronary flow post-PCI (<3)c	2	4	2	4	0.77
Laboratory results
White blood cellsc, ×109/l	11	10–15	11	10–13	0.86
Estimated Glomerular Filtration Ratec, ml/min/1.73m2	88	77–90	90	78–90	0.47
Creatine kinasec, U/l	1493	786–2400	1584	867–2570	0.75
Troponinc,	50,000	16,441–50,000	50,000	48,335–50,000	0.34
HBA1cc, mmol/mol	41	36–44	40	36–44	0.77
Infarct characteristics
Infarct size, volume in %	30	17	26	12	0.42
Area at risk, volume in %	49	19	46	17	0.46
Presence of Microvascular Obstruction (MVO)	13	59	16	57	0.89

^aKillip classification of heart failure after acute myocardial infarction: class I = no heart failure; class II = pulmonary rales or crepitations, a third heart sound, and elevated jugular venous pressure; class III = acute pulmonary edema; and class IV = cardiogenic shock

^bMulti-vessel coronary artery disease was defined according to the number of stenoses of at least 50% of the reference vessel diameter by visual assessment and whether or not there was left main stem involvement

Abbreviations: BMI = body mass index; CMR = cardiac magnetic resonance; CP = chest pain; ECV = extracellular volume; HBA1c = glycated haemoglobin; PCI = percutaneous coronary intervention; STEMI = ST-segment elevation myocardial infarction; TIMI = Thrombolysis In Myocardial Infarction

^cNon-normally distributed