Table 2.
Baseline and follow-up CMR parameters
| Acute CMR | Follow-up CMR | P-valuea | |||
|---|---|---|---|---|---|
| Median | 25%–75% quartiles | Median | 25%–75% quartiles | ||
| Baseline CMR characteristics | |||||
| LVEDVi, ml/m2 | 79.1 | 71–87 | 80.45 | 70–89 | 0.41 |
| LVESVi, ml/m2 | 42 | 36–50 | 38.7 | 31–47 | 0.02 |
| LV MASSi, grams/m2 | 55.45 | 48–64 | 48.55 | 43–55 | <0.0001 |
| EF, % | 45.65 | 36–51 | 52.35 | 43–59 | <0.0001 |
| IS, volume in % | 23.9 | 17–38 | 13.75 | 9–27 | <0.0001 |
| Segmental myocardial tissue composition and function | |||||
| Median | 25% - 75% Quartiles | Median | 25% - 75% Quartiles | ||
| Normal ECV, % (n = 325) |
27.5 | 24.8–3 0.5 | 27.7 | 25.2–32 | 0.03 |
| Oedema ECV, % (n = 246) |
34 | 29–39.3 | 32 | 28–37 | 0.0002 |
| Infarct ECV, % (n = 229) |
44 | 37.4–49 | 41 | 33.6–46 | <0.0001 |
| Normal WT (mm) (n = 325) |
3.7 | 2.7–4.8 | 3.8 | 2.0–4.7 | 0.81 |
| Oedema WT (mm) (n = 246) |
2.9 | 1.8–4.3 | 3.3 | 2.4–4.3 | 0.02 |
| Infarct WT (mm) (n = 229) |
1.6 | 0.47–2.8 | 2.4 | 1.1–3.6 | <0.0001 |
| Normal EDT (mm) | 7.3 | 6–8 | 6.7 | 6–7.5 | <0.0001 |
| Oedema EDT (mm) | 7.4 | 6–8.5 | 6.5 | 5–7.6 | <0.0001 |
| Infarct EDT (mm) | 7.9 | 7–9 | 6.4 | 56–7.6 | <0.0001 |
| Global myocardial tissue composition | |||||
| Total LV myocyte volume, mL/m2 | 51.2 | 45.7–57.4 | 53.6 | 46.3–61 | 0.14 |
| Total LV extracellular matrix, ml/m2 | 25.8 | 22.7–32.8 | 26.1 | 21.8–32.8 | 0.68 |
LV measurements are indexed to body surface area (BSA), infarct volumes are unindexed. LVEDVi = Left ventricular end-diastolic volume (indexed), LVESVi = Left ventricular end-systolic volume (indexed), LVMi = Left ventricular mass (indexed), RS = peak systolic radial strain (%)
aWilcoxon test (paired samples)