Table 2.
Differentially expressed miRNAs between LASP and LPSP
| miRNA | LPSPa | LASPa | Log2FCb | p-valuec | FDRd | ||||
|---|---|---|---|---|---|---|---|---|---|
| B1 | B2 | Q2 | Q1 | T1 | T2 | ||||
| sof-miRN167-3p | 0 | 0 | 0 | 14.331 | 0.177 | 0 | 8.451 | 5.50E-17 | 5.01E-15 |
| sof-miR167b-5p | 23.223 | 0.595 | 11.448 | 807.81 | 63.317 | 135.635 | 4.471 | 6.69E-25 | 1.83E-22 |
| sof-miR167c-5p | 24.996 | 1.444 | 9.526 | 822.728 | 64.377 | 130.387 | 4.433 | 1.50E-24 | 2.15E-22 |
| sof-miR167a-5p | 24.996 | 1.444 | 9.526 | 821.722 | 64.2 | 129.853 | 4.430 | 1.57E-24 | 2.15E-22 |
| sof-miR408-3p | 0.422 | 0.17 | 0.836 | 18.186 | 5.387 | 11.562 | 4.126 | 2.64E-16 | 2.06E-14 |
| sof-miR167b-3p | 2.027 | 0.085 | 1.421 | 21.79 | 6.535 | 43.759 | 4.042 | 5.59E-19 | 6.12E-17 |
| sof-miR167a-3p | 3.378 | 1.019 | 0.251 | 30.673 | 6.358 | 28.372 | 3.355 | 4.40E-14 | 2.19E-12 |
| sof-miR156-5p | 34.454 | 15.712 | 60.25 | 1288.775 | 76.917 | 230.445 | 3.317 | 5.85E-16 | 4.00E-14 |
| sof-miR396b-5p | 654.118 | 30.491 | 108.299 | 6328.725 | 927.242 | 1603.601 | 3.166 | 6.63E-15 | 4.01E-13 |
| sof-miR396a-5p | 655.3 | 30.491 | 108.968 | 6310.874 | 927.153 | 1603.868 | 3.160 | 7.32E-15 | 4.01E-13 |
| sof-miR396c-3p | 3.124 | 0 | 1.17 | 25.812 | 4.857 | 6.848 | 2.721 | 2.06E-10 | 8.68E-09 |
| sof-miRN375-3p | 3.124 | 0 | 1.17 | 25.812 | 4.857 | 6.848 | 2.721 | 2.06E-10 | 8.68E-09 |
| sof-miR395c-5p | 1.942 | 0.934 | 1.671 | 5.615 | 9.184 | 12.541 | 2.178 | 6.80E-07 | 1.62E-05 |
| sof-miR395a-3p | 1.942 | 1.104 | 1.671 | 5.615 | 9.184 | 12.541 | 2.106 | 1.68E-06 | 3.84E-05 |
| sof-miR395b-5p | 1.942 | 1.104 | 1.671 | 5.447 | 8.036 | 12.541 | 2.036 | 3.71E-06 | 7.51E-05 |
| sof-miR156-3p | 0.338 | 0.51 | 0.585 | 5.783 | 1.06 | 0.889 | 1.816 | 0.001132 | 0.009671 |
| sof-miRN145-3p | 1.351 | 0.595 | 0.084 | 0.084 | 9.449 | 0.089 | 1.807 | 0.000279 | 0.003154 |
| sof-miRN267-5p | 2.364 | 0 | 0.752 | 7.878 | 2.561 | 3.38 | 1.765 | 4.95E-05 | 0.000714 |
| sof-miR5384-3p | 1.52 | 0 | 0.836 | 9.638 | 0 | 1.067 | 1.693 | 0.000205 | 0.002547 |
| sof-miRN054-3p | 19 | 14.014 | 8.022 | 115.904 | 19.516 | 63.771 | 1.634 | 3.06E-05 | 0.000507 |
| sof-miR171c-3p | 25.165 | 0.679 | 2.507 | 80.119 | 6.8 | 8.005 | 1.378 | 0.000357 | 0.003909 |
| sof-miR166d-5p | 4.222 | 1.274 | 3.51 | 20.533 | 3.797 | 7.649 | 1.352 | 0.001059 | 0.009198 |
| sof-miR393-3p | 9.289 | 3.142 | 5.933 | 30.17 | 10.509 | 21.079 | 1.306 | 0.001004 | 0.009006 |
| sof-miR393-5p | 45.516 | 11.975 | 24.651 | 150.433 | 31.261 | 83.426 | 1.261 | 0.000992 | 0.009006 |
| sof-miRN014-3p | 0 | 0.425 | 3.844 | 6.788 | 6.711 | 0.356 | 1.219 | 0.006096 | 0.040176 |
| sof-miRN164-5p | 14.187 | 7.134 | 8.189 | 0 | 5.652 | 9.872 | −1.307 | 0.001391 | 0.011189 |
| sof-miRN060-3p | 8.445 | 9.682 | 8.858 | 5.531 | 4.592 | 4.091 | −1.543 | 0.000147 | 0.001867 |
| sof-miRN141-3p | 33.272 | 1.529 | 18.551 | 0 | 0 | 18.411 | −1.631 | 5.92E-05 | 0.00083 |
| sof-miRN097-5p | 45.094 | 23.866 | 23.147 | 24.639 | 7.948 | 10.05 | −1.678 | 1.79E-05 | 0.000326 |
| sof-miR166e-5p | 31.583 | 5.606 | 17.465 | 1.257 | 7.241 | 10.94 | −1.728 | 1.86E-05 | 0.000328 |
| sof-miRN003-5p | 5.236 | 0.085 | 0.501 | 0.251 | 0.177 | 1.512 | −1.814 | 0.001153 | 0.009704 |
| sof-miRN377-5p | 1.013 | 10.277 | 0.836 | 1.341 | 2.384 | 1.779 | −2.094 | 1.86E-06 | 4.08E-05 |
| sof-miR166g-5p | 56.325 | 17.241 | 59.498 | 2.179 | 9.537 | 25.437 | −2.103 | 1.23E-07 | 3.53E-06 |
| sof-miR159-5p | 7.6 | 14.863 | 24.651 | 10.392 | 0.442 | 6.226 | −2.106 | 1.93E-07 | 5.02E-06 |
| sof-miRN207-5p | 7.093 | 15.797 | 15.961 | 5.28 | 3.444 | 3.113 | −2.406 | 6.38E-09 | 2.33E-07 |
| sof-miRN245-5p | 0.084 | 7.134 | 1.086 | 0.503 | 0.883 | 1.334 | −2.529 | 1.64E-07 | 4.50E-06 |
| sof-miRN303-5p | 1.013 | 11.975 | 0.084 | 0.587 | 2.384 | 1.512 | −2.534 | 2.08E-08 | 7.10E-07 |
| sof-miR319-3p | 404.58 | 1660.938 | 5.766 | 163.842 | 1.325 | 1.512 | −4.864 | 1.95E-28 | 1.07E-25 |
aNormalized miRNA expression, > 5 in one of the six samples
bLog 2 fold change, > 1 or <− 1
cP-value calculated by edgeR, < 0.05
dFalse discovery rate, < 0.05