Table 1.
Characteristics of the included studies.
| Study ID | Sample size (T/C) | Diagnosis criteria | Intervention | Control | Course of treatment | Outcome assessment |
|---|---|---|---|---|---|---|
| Song et al., 2009 [30] | 68 (34/34) | CRGNDTCM (including gastroscopy and pathology diagnosis) |
Modified SJZD + control | Metronidazole (200 mg, twice a day), 1 week, and folate (10 mg, three times a day), 24 weeks | 24 weeks | Overall effect rate |
|
| ||||||
| Hu, 2011 [31] | 96 (48/48) | CRGNDTCM (including gastroscopy and pathology diagnosis) |
Modified SJZD | Domperidone (10 mg, three times a day), colloidal bismuth pectin (200 mg, four times a day), and omeprazole (20 mg, twice a day) | 4 weeks | Overall effect rate Hp clearance rate |
|
| ||||||
| Sun et al., 2012 [32] | 70 (36/34) | CRGNDTCM (including gastroscopy and pathology diagnosis) | Modified SJZD + control | Omeprazole (30 mg, once a day) and colloidal bismuth pectin (120 mg, three times a day) Abdominal distension or regurgitation onset: domperidone (10 mg, three times a day) HP infection: amoxicillin (500 mg, three times a day) and tinidazole (1 g, three times a day) |
3 weeks | Overall effect rate |
|
| ||||||
| Li, 2013 [33] | 126 (63/63) | Not reported | Modified SJZD + control | Bismuth potassium citrate (300 mg, three or four times a day) | Not reported | Overall effect rate |
|
| ||||||
| Zhang, 2016 [34] | 64 (32/32) | Gastroscopy diagnosis: DCBDACMA Pathology diagnosis: SNCMCG |
Modified SJZD + control | Omeprazole (20 mg, twice a day), clarithromycin (0.5 g, once a day), amoxicillin (1 g, twice a day), 14 days; and folate (10 mg, three times a day), 12 weeks | 12 weeks | Histologic grading score |
|
| ||||||
| Shen, 2016 [35] | 78 (39/39) | Not reported, but mentioned pathological examination with the help of gastroscopy | Modified SJZD + control | Metronidazole (400 mg, twice a day), Lansoprazole (30 mg, twice a day), and Levofloxacin (200 mg, twice a day) | 12 weeks | Overall effect rate |
T: treatment group; C: control group; CRGNDTCM: clinical research guideline on new drugs of traditional Chinese medicine; DCBDACMA: diagnosis criterion of Chinese digestive endoscopy association; SNCMCG: second national consensus meeting on chronic gastritis in China; SJZD: Sijunzi decoction.