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. 2016 Aug 4;8:1–5. doi: 10.1016/j.bbrep.2016.07.021

Table 1.

Literature review of murine models of hepatic breast cancer. The table states the cell lines for various murine models of breast cancer hepatic metastasis as well as the purpose of each study.

Cell Line Mouse Inoculation site Liver met? Other met? Study purpose Reference
MDA-MB-435 Female nude Mammary fat pad Yes Yes Use of surgical orthotopic implantation [7]
MDA-MB-435 Female athymic NU/NU Right second mammary gland Yes Yes Optical imaging [8]
4T1 Female BALB/c Mammary fat pad Yes Yes Effect of bisphosphonate [9]
4T1 Female BALB/c Mammary fat pad Yes Yes Effect of factor 4 [10]
4T1 Female BALB/c Mammary fat pad Yes Yes Use of dabigatran [11]
4T1 Female BALB/c Mammary fat pad Yes Yes Effect of R428 [12]
4T1 BALB/cfC3H Mammary fat pad Yes Yes Imaging [13]
4T1/luc BALB/c Mammary fat pad Yes Yes Effect of zoledronic acid [14]
MDA-MB-231 Female NCr nu/nu Mammary fat pad Yes Yes Effect of pro-matrix metalloproteinase-2 [15]
MDA-MB-231 Female athymic nude Mammary fat pad Yes Yes Effect of GLV-1h153 in TNBC [16]
MDA-MB-231 BALB/cAnN.CG-Foxn1 nu/CrINar Tail vein Yes No Effect of VP1 [17]
MDA-MB-231 Mammary pat Yes Yes Effect of PEDF [18]
MDA-MB-231 Female nude Mammary fat pad Yes Yes Effect of CH50 [19]
MDA-MB-231/luc Female Rag2-/-II2rg-/- Mammary fat pad Yes Yes Effect of phenytoin on TNBC [20]
4TLM BALB-c Right upper mammary gland Yes Yes Multi metastatic model [21]
4THM BALB-c Second right chest mammary pad Yes Yes Effect of semapimod [22]