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. 2017 Sep 20;16:1536012117717852. doi: 10.1177/1536012117717852

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 10. — Proposed mechanism of irreversible inhibition of STS by a sulfonamide through imine N-sulfate formation with the active-site formylglycine residue.⁶² STS indicates steroid sulfatase.