Skip to main content
. 2017 Jul 26;96(11):1184–1191. doi: 10.1177/0022034517703580

Figure 1.

Figure 1.

Stages of mouse palate development. (A–C) Representative hematoxylin and eosin (HE)–stained coronal sections through the middle of the anterior-posterior axis of the developing palatal shelves at E13.5 (A), E14.0 (B), and E14.5 (C). p, palatal shelf; t, tongue. Dashed box in C marks the region shown in higher magnification in D. (D, E) Higher magnification views of HE-stained coronal sections through the middle of the palatal shelves undergoing fusion at E14.5 (D) and E15.5 (E). Arrows in D point to the epithelial triangles formed from displacement of epithelial cells in the oronasal axis during formation of the midline epithelial seam (MES). Arrowhead in D points to the single cell layer MES at the midline. Arrows in E point to epithelial islands during MES dissolution. Scale bars: 100 µm.