Table 1.

Nine cases of infective endocarditis caused by Mycoplasmataceae

Patient (reference)	Age, sex	Underlying condition(s)	Valve(s)	Symptom(s)	Diagnostic tool	Pathogen	Surgery	Antibiotic therapy (duration, weeks)	Outcome
1 7	33, M	Mitral valve plasty	Mitral	Heart failure	PCR from cardiac valve	M. hominis	Y	Amo and genta (3); Doxy (4)	Survival
2 7	57, F	Prosthetic aortic valve	Aortic	Heart failure	PCR from cardiac valve	U. urealyticum	Y	Vanco (8); Genta (2)	Death
3 9	21, M	RHD; dental extraction without antibiotic prophylaxis 4 weeks before hospitalisation	Mitral	Fever, anorexia, sore throat, malaise	Serology	M.  pneumoniae	N	Benz and genta (6); Oxy (4)	Survival
4 10	25, F	SLE treated with corticosteroids; Streptococcus sanguis endocarditis; prosthetic aortic and mitral valves	Aortic and mitral	Fever	Culture from a portion of valve	M. hominis	Y	Clin and rif (6); Doxy (4)	Survival
5 11	40, M	RHD, aortic and mitral replacement	Aortic and mitral	Abdominal pain, jaundice, fever	16S rDNA PCR, culture	M. hominis	Y	Doxy and clin (8)	Survival
6 12	74, M	Aortic and mitral valve replacement	Aortic	Dizziness, cardiac and kidney failure	16S rDNA PCR, culture	M. hominis	Y	Doxy and clin (9)	Survival
7 13	57, M	Aortic valve replacement, aortic root and mitral repair	Aortic	Dyspnoea, fatigue, chest pain	16S rDNA PCR	M. hominis	Y	Doxy and clin (9)	Survival
8 8	46, M	Mitral valve replacement	Mitral	Dyspnoea, heart failure	Culture	M. hominis	Y	Vanco and amika	Death
9 (PR)	56, M	s/p lymphoma, s/p septic arthritis with U. parvum	Aortic	Dyspnoea, heart failure	PCR from cardiac valve	U. parvum	Y	Doxy (8)	Survival (15 months after surgery)

Amika, amikacin, Amo, amoxicillin, Benz, benzylpenicillin, Clin, clindamycin, Doxy, doxycycline, Genta, gentamicin, Oxy, oxytetracycline, PR, present report, RHD, rheumatic heart disease, Rif, rifampin, SLE, systemic lupus erythematosus, s/p, status post, Vanco, vancomycin