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. 2017 Oct 1;8(5):531–545. doi: 10.14336/AD.2017.0520

Figure 1. Lipid profiles are altered in the forebrains of aged mice by dietary PUFA supplementation.

Figure 1.

Mice were maintained on a low n-3 PUFA (N3L) or high n-3 PUFA (N3H) diet for 3 months, and forebrains were then processed for lipid analysis. (A) Lipid profiles in mouse forebrains expressed as the percent of total fatty acids (TFA), and included profiles of saturated fatty acids (SFA), mono-unsaturated fatty acids (MUFA), and poly-unsaturated fatty acids (PUFA). (B) The ratio of forebrain n-3 to n-6 fatty acids increased in N3H-fed mice. (C) Specific n-3 PUFAs content expressed as pmol/mg; the n-3 PUFAs include α-linolenic acid (ALA), docosapentaenoic acid (DPA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). (D) Specific n-6 PUFAs content expressed as pmol/mg: the n-6 PUFAs include arachidonic acid (AA), docosatetraenoic acid (DTA), dihomo-γ-linolenic acid (DGLA) and γ-linoleic acid (GLA). Data are mean ± SEM, n=4 per group; *p≤0.05, **p≤0.01 vs. N3L.