Table 2. Regression analyses of SP, GR, 11βHSD mRNA expression against birth weight and weight at 21 days and SP mRNA expression against plasma cortisol concentrations on postnatal day 20.
Variables | Equation | N | Adjusted r2 | P |
---|---|---|---|---|
SP mRNA expression (MNE) vs. Birth weight (kg) | ||||
SP-A | y = 1.84x – 0.23 | 14 | 0.565 | 0.001 |
SP-B | 14 | 0.205 | 0.059 | |
SP-C | 14 | 0.108 | 0.135 | |
SP-D | 14 | 0.099 | 0.145 | |
GR, 11βHSD mRNA expression (MNE) and plasma cortisol vs. Birth weight (kg) | ||||
GR | y = 0.19x – 0.015 | 14 | 0.489 | 0.003 |
11βHSD-1 | 13 | 0.191 | 0.076 | |
11βHSD-2 | 13 | 0.016 | 0.292 | |
Plasma cortisol concentration | 9 | 0.413 | 0.062 | |
Lung tissue cortisol concentration | 11 | -0.0120 | 0.372 | |
SP mRNA expression (MNE) vs. Weight at 21 days (kg) | ||||
SP-A | y = 2.09x – 0.012 | 15 | 0.356 | 0.011 |
SP-B | 15 | 0.169 | 0.071 | |
SP-C | 15 | 0.049 | 0.212 | |
SP-D | 15 | -0.026 | 0.436 | |
GR, 11βHSD mRNA expression (MNE) and plasma cortisol vs. Weight at 21 days (kg) | ||||
GR | y = 0.228x – 0.001 | 14 | 0.582 | 0.001 |
11βHSD-1 | 13 | 0.092 | 0.292 | |
11βHSD-2 | 14 | 0.051 | 0.217 | |
Plasma cortisol concentration | 10 | 0.079 | 0.219 | |
Lung tissue cortisol concentration | 11 | -0.0976 | 0.747 | |
SP mRNA expression (MNE) vs plasma cortisol concentration | ||||
SP-A | 10 | 0.051 | 0.259 | |
SP-B | 10 | 0.006 | 0.830 | |
SP-C | 10 | 0.156 | 0.259 | |
SP-D | 10 | 1.34E-005 | 0.992 | |
SP mRNA expression (MNE) vs lung tissue cortisol concentration | ||||
SP-A | 10 | 0.146 | 0.150 | |
SP-B | 10 | 0.038 | 0.278 | |
SP-C | y = 0.34x + 2.27 | 10 | 0.446 | 0.021 |
SP-D | y = 0.0092x + 0.026 | 10 | 0.4522 | 0.020 |
Regression equations are only provided in case of significant relationships. MNE, mean normalised expression.