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. Author manuscript; available in PMC: 2017 Dec 19.
Published in final edited form as: Chem Res Toxicol. 2016 Nov 7;29(12):2008–2039. doi: 10.1021/acs.chemrestox.6b00265

Figure 6.

Figure 6

Inflammation-induced formation of hypochlorous acid (HOCl) and hypobromous acid (HOBR) and major nucleobase halogenation products. Myeloperoxidase can induce the formation of both HOCl and HOBr. The mechanism for the formation of HOBr by myeloperoxidase is different from that by eosinophil peroxidase.