Table 4. Repair Mechanisms of Oxidative Stress-Induced DNA Lesions.
DNA lesions/modifications | repair pathways | refs |
---|---|---|
8-oxo-dG | BER | 25,27,188–190 |
8-oxo-dA | BER | 25,27,188–190 |
Fapy-dG | BER | 25,27,188–190 |
Fapy-dA | BER | 25,27,188–190 |
dGh | BER | 193,195–198 |
dSp | BER | 193,195–198 |
thymidine glycol | BER | 206,207,210 |
NER | 211 | |
5-hmdU | BER | 188,219,220 |
5-fdU | BER | 228,230–236 |
5-fdC | BER | 65,220,246,247 |
5-cadC | BER | 65,220,246,247 |
R/S-cdA | NER | 86,91,249,250 |
R/S-cdG | NER | 86,91 |
d(G[8-5]C) | NER | 257 |
d(G[8-5m]T) | NER | 256,257,332 |
d(G[8-N3]T) | NER | 259 |
BER | 260 | |
8-Cl-dG | BER | 262 |
5-Cl-dU | BER | 263 |
dNIm | BER | 199 |
εdA | AlkB/ALKBH | 281,282 |
BER | 281 | |
εdC | AlkB/ALKBH | 281,282 |
BER | 281 | |
1,N2-εG/1,N2-εdG | AlkB/ALKBH | 281,282 |
BER | 281 | |
N2,3-εG/N2,3-εdG | AlkB/ALKBH | 282 |
281 | ||
BER | 281 | |
M1dG | AlkB/ALKBH | 287 |
NER | 14 | |
Acr-dG | AlkB/ALKBH | 287 |
NER | 14 | |
Cro-dG | NER | 14 |