Effect of GTCs, EGCG, EGC and GA on learning in aged SAMP10 mice. The learning time of SAMP10 mice was examined using a step-through test system. The time needed to acquire the avoidance response was measured in mice that ingested GTCs, EGCG, EGC and GA (black or gray columns) and in control mice (open column). Each value represents the mean±SEM (n=8–23). Asterisks represent a significant difference (* p<0.05, Bonferroni's t-test).