Table 1. Summary of results from P1 animals.
| INOCULA | CLINICAL1 | RT-QUIC1 | WESTERN BLOT1 | HISTOLOGY1 | ||||
|---|---|---|---|---|---|---|---|---|
| Ha2 | Tg7 Mice | Ha | Tg7 Mice | Ha | Tg7 Mice | Ha | Tg7 Mice | |
| NBH(WT)RTQ 1:1 | 0/6# | 0/4 | 0/6 | 0/4 | 0/1 | 0/1 | 0/4 | 0/4 |
| NBH(WT)RTQ 1:10 | 0/6 | 0/4 | 0/6 | 0/4 | 0/1 | 0/1 | 0/6 | 0/4 |
| NBH(K4N)RTQ 1:1 | 0/6 | 0/4 | 0/5 | 0/4 | 0/1 | 0/1 | 0/3 | 0/4 |
| NBH(K4N)RTQ 1:10 | 0/6 | 0/6 | 0/5 | 0/6 | 0/1 | 0/1 | 0/5 | 0/2 |
| ScBH(WT)RTQ 1:1 | 0/6 | 0/6 | 6/6 | 6/6 | 0/6 | 1/6 | 0/4 | 4/6* |
| ScBH(WT)RTQ 1:10 | 0/6 | 0/6 | 6/6 | 6/6 | 0/1 | 0/6 | 0/5 | 0/6 |
| ScBH(K4N)RTQ 1:1 | 0/6 | 0/4 | 6/6 | 4/4 | 1/6 | 4/4 | 3/4 | 4/4 |
| ScBH(K4N)RTQ 1:10 | 0/6 | 0/2 | 6/6 | 0/2 | 0/1 | 0/1 | 0/6 | 0/2 |
| ScBH(K4A)RTQ 1:1 | 0/5 | NA | 5/5 | NA | 0/5 | NA | 2/5 | NA |
| ScBH seed only 1:1 | 0/6 | 0/4 | 0/4 | 0/4 | 0/1 | 0/2 | 0/2 | 0/4 |
| NBH seed only 1:1 | 0/6 | NA | 0/4 | NA | 0/1 | NA | 0/2 | NA |
| Uninoculated | 0/4 | NA | 0/4 | NA | 0/3 | NA | 0/1 | NA |
#number positive/total animals surveyed;
*Three animals showed mild astrogliosis but no other histopathology;
1Animals were scored positive based on the criteria outlined in the methods;
2Hamsters