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Photomicrograph of liver section after dermal administration showing (A control): normal liver architecture, hepatocytes, central venules, sinusoids without infiltration of inflammatory cells. B,C (1000, 2000 mg/kg bwt p-DNB): poor liver architecture, aggregating inflammatory cells, liver parenchyma with fibrosis and hepatic necrosis, severe micro vesicular steatosis with the fat infiltration within the cytoplasms. (X400).
