Table 3.
Average OHIP-143 responses of survivors of breast cancer treated with aromatase inhibitor (AI) vs. women without cancer diagnoses at the 4 points in time
| How often in the last month, have you | AI use | Base Line1 | 6 months | 12 months | 18 months | P(Tx)/P(Time) P(int)2 |
|---|---|---|---|---|---|---|
| - had trouble pronouncing any words because of problems with your teeth or mouth? | No | 1.07 | 1.03 | 1.03 | 1.07 | .195/.629 .629 |
| AI | 1.26 | 1.22 | 1.22 | 1.17 | ||
| - felt that your sense of taste has worsened because of problems with your teeth or mouth? | No | 1.03 | 1.00 | 1.00 | 1.00 | .052/.002 .019 |
| AI | 1.45 | 1.13 | 1.17 | 1.04 | ||
| - had painful aching in your mouth? | No | 1.03 | 1.17 | 1.17 | 1.17 | .145/.515 .687 |
| AI | 1.41 | 1.48 | 1.35 | 1.22 | ||
| - felt tense because of problems with your teeth or mouth? | No | 1.07 | 1.21 | 1.18 | 1.04 | .050/.055 .027 |
| AI | 1.62 | 1.30 | 1.17 | 1.12 | ||
| - found it uncomfortable to eat any foods because of problems with your teeth or mouth? | No | 1.10 | 1.14 | 1.07 | 1.07 | .093/.076 .840 |
| AI | 1.65 | 1.48 | 1.30 | 1.26 | ||
| Has your diet been unsatisfactory because of problems with your teeth or mouth? | No | 1.00 | 1.03 | 1.00 | 1.00 | .063/.090 .060 |
| AI | 1.17 | 1.13 | 1.09 | 1.13 | ||
| - been self-conscious because of your teeth or mouth? | No | 1.07 | 1.14 | 1.14 | 1.11 | .017/.936 .017 |
| AI | 1.48 | 1.52 | 1.48 | 1.43 | ||
| - found it difficult to relax because of problems with your teeth or mouth? | No | 1.10 | 1.10 | 1.03 | 1.14 | .615/.203 .025 |
| AI | 1.22 | 1.13 | 1.04 | 1.17 | ||
| - had to interrupt meals because of problems with your teeth or mouth? | No | 1.07 | 1.03 | 1.00 | 1.10 | .092/.123 .141 |
| AI | 1.39 | 1.26 | 1.09 | 1.22 | ||
| - been a bit irritable with other people because of problems with your teeth or mouth? | No | 1.00 | 1.00 | 1.00 | 1.03 | .035/.017 .231 |
| AI | 1.27 | 1.00 | 1.05 | 1.09 | ||
| - been embarrassed because of problems with your teeth or mouth? | No | 1.00 | 1.14 | 1.10 | 1.10 | .061/.444 .016 |
| AI | 1.26 | 1.37 | 1.39 | 1.40 | ||
| - had difficulty doing your usual tasks because of problems with teeth and mouth? | No | 1.00 | 1.00 | 1.00 | 1.00 | .011/.288 .097 |
| AI | 1.14 | 1.04 | 1.05 | 1.10 | ||
| - felt that life in general was less satisfying because of problems with your teeth and mouth? | No | 1.03 | 1.00 | 1.00 | 1.00 | .072/.263 .061 |
| AI | 1.17 | 1.22 | 1.02 | 1.13 | ||
| - been totally unable to function because of problems with your teeth and mouth? | No | 1.00 | 1.00 | 1.03 | 1.0 | .350/.662 .020 |
| AI | 1.14 | 1.03 | 1.10 | 1.10 |
1
Answers ranged from 1 = “Never”, 2 = “Hardly ever”, 3 = “On occasion”, 4 = “Fairly often”, to 5 = “Very often”.
2
The average responses to these questions were compared with repeated measurement univariate analyses of variance. P(Tx) is the p-value for “Treatment” AI use vs. control group; P(Time) is the p-value for the main effect “Time” Baseline vs. 6 month vs. 12month vs. 18month visits; P(int) is the p value of interaction effect between “Treatment” × “Time”.
3
OHIP-14- Oral Health Oral Health Impact Profile 14- item short form