Fig. 8.

Level of hypoxia inducing factor – 1 alpha (HIF-1α) and parasite viability. [A] Level of HIF-1α determined in the absence of Toxoplasma gondii infection after a 24-h treatment; [B] Level of HIF-1α determined in the presence of Toxoplasma gondii infection after a 24-h treatment; [C] Toxoplasma gondii viability determined after a 48-h treatment with 3-(5′-Hydroxymethyl-2′-furyl)-1-benzyl indazole (YC-1) and CoCl₂. Data are expressed as the mean ± SEM. The experiment was performed in triplicate and repeated three times independently. α is significant at p < 0.05 versus control (no infection), β at p < 0.001 versus control (no infection), γ at p < 0.0001 versus infection only. ‘hpi’ is hours post-infection.