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. 2017 Sep 25;4(6):e395. doi: 10.1212/NXI.0000000000000395

Figure 1. Representative MRIs from select children with RIS.

Figure 1

Axial FLAIR images demonstrate (A) an infratentorial hyperintensity within the cerebellar white matter in a child with RIS at baseline (other lesions not shown) and (B) juxtacortical and ovoid hyperintensities (arrows) in a different child. (C) Sagittal FLAIR image from the child shown in B demonstrates hyperintensities extending over the long axis of the lateral ventricles and oriented perpendicularly to the corpus callosum (arrows, other lesions not shown). To date, neither child has developed a first clinical event consistent with CNS demyelination. RIS = radiologically isolated syndrome; FLAIR = fluid-attenuated inversion recovery.