Table 1.
Patient characteristics
| Characteristics | CAR | NCAR | p-value |
|---|---|---|---|
| Number of patients | 23 | 30 | |
| Demographic data | |||
| Age, years | 64.8±8.4 | 69.4±8.2 | NS* |
| Sex, male/female | 16/7 | 22/8 | NS |
| Body weight, kg | 80.4±13.3 | 81.5±11.2 | NS |
| Height, cm | 172.3±8.4 | 172.2±8.6 | NS |
| BMI, kg/m2 | 27.0±3.5 | 27.7±3.6 | NS |
| BSA, m2 | 1.9±0.2 | 2.0±0.2 | NS |
| Medical conditions | |||
| Hypertension | 14 (61) | 25 (83) | NS |
| Coronary artery disease | 2 (9) | 8 (27) | NS |
| Chronic heart failure | 0 (0) | 2 (7) | NS |
| History of MI | 0 (0) | 6 (20) | 0.0303 |
| Atrial fibrillation | 3 (13) | 3 (10) | NS |
| Diabetes mellitus | 1 (4) | 11 (37) | 0.0071 |
| Chronic renal failure | 0 (0) | 2 (7) | NS |
| COPD | 1 (4) | 5 (17) | NS |
| Hyperlipidemia | 4 (17) | 18 (60) | 0.0022 |
| Medication | |||
| B-adrenergic blockers | 10 (43) | 12 (40) | NS |
| ACE inhibitors | 7 (30) | 11 (37) | NS |
| ARBs | 1 (4) | 6 (20) | NS |
| CCBs | 4 (17) | 12 (40) | NS |
| Diuretics | 5 (22) | 8 (27) | NS |
| Aspirin | 3 (13) | 8 (27) | NS |
| Anticoagulants | 1 (4) | 5 (17) | NS |
| Oral antidiabetics | 0 (0) | 7 (23) | 0.0148 |
| Insulin | 0 (0) | 4 (13) | NS |
| Statins | 3 (13) | 14 (47) | 0.0163 |
| ASA | |||
| II | 18 (78) | 14 (47) | 0.0255 |
| III | 5 (22) | 14 (47) | NS |
| IV | 0 (0) | 2 (7) | NS |
Notes: Data are presented as mean ± standard deviation or n (%) unless otherwise noted.
*
p>0.05.
Abbreviations: NS, not significant; CAR, cardiac autonomic reactivity; NCAR, non-cardiac autonomic reactivity; BMI, body mass index; BSA, body surface area; MI, myocardial infarction; COPD, chronic obstructive pulmonary disease; ACE, angiotensin-converting enzyme; ARBs, angiotensin II receptor blockers; CCBs, calcium channel blockers; ASA, American Association of Anesthesiologists physical status classification system.