Table 1.
Summary of demographic and basic clinical data for all groups.
| Diagnosis | Controls n = 69 |
bvFTD n = 27 |
nfvPPA n = 14 |
svPPA n = 19 |
AD n = 19 |
ANOVA n = 148 | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||
| Smx onset (age) | N/A | N/A | 53.56 | 7.54 | 63.14 | 5.39 | 57.11 | 8.91 | 55.79 | 9.20 | p = 0.0058⁎ |
| Disease duration, baseline, yr | N/A | N/A | 5.87 | 4.11 | 4.86 | 3.46 | 5.84 | 3.01 | 5.00 | 2.37 | p = 0.6987 |
| Age at baseline scan, yr | 64.19 | 6.70 | 59.43 | 6.84 | 68.00 | 7.18 | 62.95 | 7.12 | 60.79 | 9.01 | p = 0.0025⁎ |
| Follow-up scan (age) | 65.36 | 7.03 | 60.38 | 6.80 | 68.95 | 7.30 | 63.90 | 7.10 | 62.09 | 8.92 | p = 0.0031⁎ |
| Interscan interval, yr | 1.17 | 0.60 | 0.95 | 0.22 | 0.95 | 0.35 | 0.95 | 0.37 | 1.30 | 0.47 | p = 0.0387⁎ |
| Sex, M/F, # | 1.52 | 0.50 | 1.41 | 0.50 | 1.43 | 0.51 | 1.58 | 0.51 | 1.53 | 0.51 | p = 0.7671 |
| Education, yr | 17.59 | 1.94 | 15.78 | 2.95 | 16.46 | 2.79 | 16.50 | 2.71 | 16.83 | 3.22 | p = 0.0262⁎ |
| MMSE baseline | 29.52 | 0.68 | 24.81 | 3.62 | 23.64 | 8.44 | 22.42 | 7.86 | 21.94 | 6.16 | p < 0.00001⁎ |
| MMSE follow-up | 27.98 | 7.29 | 19.78 | 9.94 | 18.08 | 12.23 | 18.89 | 6.98 | 14.26 | 10.96 | p < 0.00001⁎ |
| CDRTot baseline | 0.00 | 0.00 | 6.80 | 2.80 | 2.40 | 2.60 | 4.10 | 1.80 | 5.30 | 0.40 | p < 0.0001⁎ |
| CDRBox baseline | 0.00 | 0.00 | 1.20 | 0.60 | 0.50 | 0.50 | 0.70 | 0.40 | 0.90 | 2.00 | p < 0.0001⁎ |
| CDRTot follow-up | 0.00 | 0.00 | 8.50 | 3.00 | 3.40 | 3.80 | 5.50 | 2.70 | 5.60 | 3.90 | p < 0.0001⁎ |
| CDRBox follow-up | 0.00 | 0.00 | 1.50 | 0.60 | 0.70 | 0.60 | 1.00 | 0.50 | 0.70 | 1.50 | p < 0.0001⁎ |
bvFTD, behavioral variant frontotemporal dementia; nvfPPA, non-fluent/agrammatic primary progressive aphasia; svPPA, semantic variant primary progressive aphasia, AD, Alzheimer's disease; ANOVA, analysis of variance; Smx, symptom; yr, years; M, male; F, female; MMSE, Mini-Mental State Examination score; CDRTot, clinical dementia rating score total; CDRBox, CDR box score.
⁎
Significant differences p < 0.05.