Table 5.

Secondary dichotomous outcome results

	Adjusted odds ratio*(95% CI)	p value
Ultra-high risk of psychosis (PQ-16)
Week 10	0·26 (0·15 to 0·46)	<0·0001
Week 22	0·33 (0·18 to 0·59)	0·00026
Mania (Altman)
Week 10	2·01 (1·48 to 2·73)	<0·0001
Week 22	1·89 (1·34 to 2·66)	0·00027
Depressive disorder (PHQ-9)
Week 10	0·21 (0·14 to 0·32)	<0·0001
Week 22	0·32 (0·21 to 0·48)	<0·0001
Anxiety disorder (GAD-7)
Week 10	0·32 (0·21 to 0·48)	<0·0001
Week 22	0·42 (0·27 to 0·64)	<0·0001
Contacted mental health services
Week 10	1·19 (0·70 to 2·04)	0·52
Week 22	0·98 (0·55 to 1·75)	0·94
Mental health diagnosis
Week 10	1·33 (0·75 to 2·37)	0·33
Week 22	1·43 (0·78 to 2·63)	0·25
Psychiatric medication
Week 10	0·77 (0·47 to 1·26)	0·30
Week 22	0·96 (0·58 to 1·59)	0·86
Psychological therapy
Week 10	1·27 (0·48 to 3·35)	0·63
Week 22	0·41 (0·11 to 1·58)	0·20

1142 participants in the control group at week 10 and 971 participants at week 22. 733 participants in the treatment group at week 10 and 603 participants at week 22. PQ-16=Prodromal Questionnaire 16-item version. PHQ-9=Patient Health Questionnaire 9-item version. GAD-7=Generalised Anxiety Disorder 7-item version.

^*Logistic mixed effects model adjusted for gender, student status, week, and interaction of week with randomisation, and including a random effect for student within university. Covariance matrix of within subject measurements was unstructured.