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. 2017 Sep 19;12:6963–6972. doi: 10.2147/IJN.S144056

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© 2017 Li et al. This work is published and licensed by Dove Medical Press Limited

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Preparation of liposomes coupled with anti-VEGF2. (A) Schematic illustration of the coupling of anti-VEGF2 to liposomes via maleimide-thiol reaction. (B) Particle size distribution of liposomes with anti-VEGF2. (C) TEM examination revealed a uniform spherical shape for the liposomes coupled with anti-VEGF2 (magnification ×5,000).

Abbreviations: Diam, diameter; Mal, maleimide; SPDP, N-succinimidyl-3-(2-pyridyldithio)propionate; TEM, transmission electron microscopy; VEGF2, vascular endothelial growth factor 2; WT, wild type.