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. 2017 Sep 19;10:2271–2280. doi: 10.2147/JPR.S139324

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© 2017 Zhi et al. This work is published and licensed by Dove Medical Press Limited

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Effect of EA at GB30 on PMWL and PMWT in CCI and CCIp rats.

Notes: (A) In either CCI (n=7) or CCIp (n=10) rats, PMWL was decreased significantly on day 5 after nerve ligation (post-model) compared to 1 day before nerve ligation (pre-model) (^***P<0.001, paired t-test). No significant difference was found between CCI and CCIp rats (unpaired t-test). EA at GB30 caused significant increase in PMWL compared to post-model (^##P<0.01, paired t-test); however, no significant difference was found between groups after EA at GB30 (unpaired t-test). (B) PMWT was significantly reduced after nerve ligation compared to one day before nerve ligation in CCI and CCIp rats (^***P<0.001, paired t-test). There was no significant difference between CCI and CCIp rats (unpaired t-test). EA at GB30 significantly augmented PMWT in both CCI (^###P<0.001, unpaired t-test) and CCIp rats (^##P<0.01, paired t-test) compared to post-model, and there was no significant difference between both groups after EA at GB30 (unpaired t-test).

Abbreviations: CCI, chronic constriction injury of the sciatic nerve; CCIp, chronic constriction injury of the partial sciatic nerve; EA, electroacupuncture; PMWL, paw mechanical withdrawal latency; PMWT, paw mechanical withdrawal threshold.