Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 19;12:6973–6984. doi: 10.2147/IJN.S139011

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Ahmed et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Overlaid in vitro MRI scans showing the difference in binding specificity and negative enhancement effect on T₂-weighted values between PC-3 and normal prostate cells RC77N/E. Both cells were treated with (A) 5 and (B) 10 pmol of NT-IONPs, LHRH-IONPs, AE105-IONPs, and LHRH-AE105-IONPs. (C) Comparison of the reduction in T₂ values between PC-3 cells and RC77N/E cells treated with IONPs. (D) T₂ maps correlated with a reduction in T₂ values.

Abbreviations: MRI, magnetic resonance imaging; NT-IONPs, non-targeted IONPs; LHRH-IONPs, luteinizing hormone-releasing hormone receptor peptide-targeted IONPs; AE105-IONPs, urokinase-type plasminogen activator receptor peptide-targeted IONPs; LHRH-AE105-IONPs, LHRH peptide- and AE105 peptide-targeted IONPs; IONPs, iron oxide nanoparticles; TE, echo time.